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Alzheimer’s Caused By Loss of Cannabinoids, Study Shows

Submitted by Marijuana News on Wed, 07/02/2014 - 09:34

Early deficits in Alzheimer’s may be caused by blockage of the brain’s cannabinoids, according to new research out of Stanford University.

Clumps of protein in the brain, called beta-amyloid plaques, are the primary marker of Alzheimer’s disease. For long, scientists knew that these clumps interfered with memory signals in the brain — but they weren’t sure how.

Now a team from Stanford University School of Medicine has traced the effects of beta-amyloid plaque to activity of the brain’s endogenous cannabinoids, or endocannabinoids. These compounds are produced naturally by the brain and mimic the effects of compounds in cannabis. Among many functions, cannabinoids play a key role in memory and learning.

“Endocannabinoids in the brain are very transient”Looking at brain slices taken from rats, the researchers observed that clumps of beta-amyloid indirectly impaired memory pathways by interfering with the normal activity of cannabinoids.

 

This interference with the brain’s cannabinoids may be...

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URL: 
http://www.leafscience.com/2014/06/23/alzheimers-caused-loss-cannabinoids-study-shows/

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