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Home 🌿 Medical Cannabis News 🌿 Seek and Destroy – How Cannabinoids Selectively Target Abnormal Cells 🌿

Seek and Destroy – How Cannabinoids Selectively Target Abnormal Cells

Submitted by Marijuana News on Tue, 08/05/2014 - 14:41

A new study in the July issue of Biochemical Pharmacology elaborates upon a unique mechanism of cannabinoids’ anti-cancer activity.  It is notable for demonstrating how cannabinoids work synergistically with the body’s immune system to stop cancer, unlike traditional treatments which destroy the immune system in the process of stopping cancer.

Researchers tested the effects of CBD, THC, and an endocannabinoid analogue called methanandamide on two lung cancer cell lines, A549 and H460, along with cells from a lung cancer patient.  It found these compounds increased expression of intercellular adhesion molecule 1 (ICAM-1) on the cancer cells, which made them more susceptible to white blood cells called lymphokine-activated killer cells (LAK).  However, normal cells were not affected this way, showing yet again that cannabinoids can selectively target abnormal cells while leaving healthy tissue alone.

LAK cells are a very powerful part of the body’s natural anti-cancer defense system.  In fact, direct...

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