Why you crave Twinkies after smoking marijuana
Researchers from Yale University believe they have deciphered the neurological mechanism that causes the “munchies,” that inexplicable urge to eat that has led generations of marijuana users to consume untold numbers of nachos, Twinkies and Doritos.
The phenomenon appears to be driven by neurons in the brain that typically involve suppressing the appetite, according to a paper published last month in the journal Nature. When responding to marijuana, however, neurons that normally turn off hunger pangs instead made users ravenous — at least when those users were transgenic lab mice.
Tamas Horvath, the study’s lead author and a Yale professor and neurobiologist, likened the reaction to hitting a car’s brakes and accelerating instead.
“It fools the brain’s central feeding system,” Horvath said in an announcement accompanying the research, which was funded in part by the National Institutes of Health and the American Diabetes Association. “We were
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