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Home 🌿 Medical Cannabis News 🌿 Scientists Produce Strongest Evidence Yet of Schizophrenia's Causes 🌿Scientists Produce Strongest Evidence Yet of Schizophrenia's Causes
Researchers discover that risk mutations disrupt a delicate chemical balance in the brain, responsible for brain development and function.
An international team of scientists led by Cardiff researchers has provided the strongest evidence yet of what causes schizophrenia - a condition that affects around 1 percent of the global population.
Published in the journal Neuron, their work presents strong evidence that disruption of a delicate chemical balance in the brain is heavily implicated in the disorder.
In the largest ever study of its kind, the team found that disease-linked mutations disrupt specific sets of genes contributing to excitatory and inhibitory signaling, the balance of which plays a crucial role in healthy brain development and function.
The breakthrough builds on two landmark studies led by members of the Cardiff team, published last year in the journal Nature.
"We're finally starting to understand what goes wrong in schizophrenia," said lead author Dr Andrew Pocklington...
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