A New Tool to Tackle Neurological Disorders
In a world first, neuroscientists at Flinders University have identified a series of chemical tools that can either increase or inhibit the release of neurotransmitters by neurons, the cells of the brain.
While not yet applied to a specific disease, the discovery has a wide range of potential pharmaceutical applications in neurological conditions ranging from schizophrenia to depression.
A team led by Associate Professor Damien Keating, a National Health and Medical Research Council (NHMRC) Research Fellow in the Department of Human Physiology and the Centre for Neuroscience at Flinders, has published a paper on the action of a protein called dynamin in the latest issue of the prestigious journal Molecular Psychiatry.
Vesicles – small spherical bodies within cells – contain active chemicals that can include neurotransmitters or hormones. Associate Professor Keating’s research is concerned with the process which sees vesicles move to the surface of a cell before opening a...
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