Inhaled Cannabis Promising for Painful Diabetic Neuropathy

Inhaled cannabis can blunt the pain of diabetic neuropathy without seriously impairing cognitive function, a new study shows.

"The higher the dose, the more the pain relief," first author Mark Wallace, MD, told Medscape Medical News. "There was, however, a dose-dependent increase in euphoria."

The study is the first randomized controlled trial of inhaled cannabis for diabetic neuropathy pain, said Dr Wallace, chair of the Division of Pain Management at the University of California, San Diego. It was published in the July issue of the Journal of Pain.

Painful diabetic neuropathy appears to be increasingly common, and currently approved medications don't provide adequate relief to most patients with this condition, Dr Wallace and his colleagues write.

A cannabinoid receptor is expressed in several regions of the nervous system. Recent studies on inhaled cannabis and neuropathic pain were promising, but none of them focused on diabetic neuropathy, the researchers note.

To fill that gap,...

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URL: 
http://www.medscape.com/viewarticle/848539