Why Runner's High Can Cause Weed-Like Effects

That may not be quite true. All this seems to suggest that cannabinoids and not, in fact, endorphins are responsible for the runner’s high as reported in PNAS.

Endocannabinoids are produced naturally in our bodies, but it’s also one of the containing molecules in cannabis, or marijuana. The endocannabinoid system is also responsible for moderating the psychoactive, feel-good effects of marijuana, the New York Times reports.

Scientists went on to the next stage during which they isolated endorphins to determine the effects of endocannabinoids.

Running is known to boost blood levels of β-endorphins, previously associated with subjective feelings of well-being often characterized as runner’s high.

But there’s a problem with this theory.

It’s known that a runner’s high isn’t actually the result of endorphins, which are too large to cross the blood-brain barrier, but scientists have long sought the elusive cause of the much-talked-about sense of euphoria...

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