Pharmaceuticals to Cure Marijuana Dependence and Abuse? You've Got to Be Kidding

Researchers looking for a drug to treat "marijuana dependence and abuse" may have found one, but the cure could be worse than the disease.

A team of scientists at Brown University conducted a pilot study to determine whether topiramate, an epilepsy drug marketed as Topamax, could be combined with motivational enhancement therapy (MET) to make MET more effective in reducing marijuana consumption.

Researchers seem to hope Topamax can be a silver bullet addiction cure. Scientists, including a member of the Brown team, have studied it as a potential treatment for alcohol and nicotine dependence and cocaine addiction, and now they are turning their sights on weed.

The pilot study consisted of 66 volunteers aged 15 to 24 who smoked at least twice weekly but who were interested in receiving both psychological and drug treatment. Some participants got Topamax alone and some got placebos, but all got MET counseling. The...

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