AKT1 Gene Could Help Identify Psychosis, Memory Loss Risk In Marijuana Users

Researchers have identified a gene which can be used to predict how susceptible a young person is to the mind-altering effects of smoking marijuana, an increasing concern as the cultural movement shifts toward legalization.  Around one percent of cannabis users develop psychosis. It is known that smoking cannabis daily doubles an individual's risk of developing a psychotic disorder, but it has been difficult to establish who is most vulnerable.  

Previous research has found a link between the AKT1 gene and people who have gone on to develop psychosis. In the new study, Celia Morgan, Professor of Psychopharmacology at the University of Exeter and Professor Val Curran and her team at University College London found that young people with variation in the 'AKT1' gene experienced visual distortions, paranoia and other psychotic-like symptoms more strongly when they were under the influence of cannabis. 

Researchers have previously found a high prevalence of...

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