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Shedding Light on Medical Marijuana: The Endocannabinoid System

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Submitted by Marijuana News on Wed, 01/28/2015 - 10:21
  • This is the third in our series on medical marijuana for bipolar. In the first piece, we made a conditional case for marijuana to treat bipolar, with some major provisos. The second piece compared the risk/benefits of medical marijuana with prescription drugs.

    In this installment, we look at the endocannabis system that marijuana acts upon.

     

    Endocannabinoids (ECs) are naturally occurring compounds throughout the brain and body that regulate cellular signaling and cellular maintenance. They function in a similar fashion to neurotransmitters such as serotonin and dopamine, except they travel backward, against the flow, from the postsynaptic cell to the presynaptic cell.

    At the presynaptic cell, the ECs dock to CR1 and CR2 cannabinoid receptors and release their chemical messages. One of the effects may be to inhibit the release of certain neurotransmitters from the presynaptic cell back to the postsynaptic cell.

    In effect,

    • ...
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URL: 
http://www.healthcentral.com/bipolar/c/15/166463/light-marijuana-endocannabinoid

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