Sickle Cell and Cannabis
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The subscription service is currently unavailable. Please try again later.Sickle cell disease (SCD) is a hereditary condition caused by a mutation in the haemoglobin gene, which leads to symptoms of anaemia, extreme pain, and organ damage if unmanaged. Individuals suffering from SCD are far more likely to use cannabis than the general population, potentially for its analgesic properties.
What is Sickle Cell Disease?
In SCD, a mutation in the haemoglobin gene causes red blood cells to become distorted, from the usual pliable, concave disc to a rigid, sickle-shaped form. In normal conditions, the cells temporarily deform in order to be squeezed through narrow blood vessels.
In SCD, the rigid cells are unable to pass, and can build up, blocking the blood vessels. This can lead to sickle cell ‘crisis’, an umbrella term for a set of acute conditions that may in extreme instances cause death within 1-2 hours. Loss of blood to the organs is one of the primary...
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