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Snorted, injected or smoked? It can affect a drug’s addictiveness

Submitted by Marijuana News on Wed, 09/02/2015 - 13:33

Many people use drugs, but not everyone becomes addicted. Why? Part of the reason comes down to how you take a drug. Are you smoking, injecting, snorting or swallowing it? That dictates how much drug gets into the brain, how fast, and how often brain levels of drug rise and fall. These are pharmacokinetic variables, and they reflect how your body absorbs and distributes a drug.

For instance, if you smoke a joint, brain levels of cannabis will both rise and decline much faster than if you had eaten the same amount of cannabis in a brownie. And a rapid rise and fall in brain levels of a drug is more likely to lead to addiction. That is why a substance can lead to addiction in one form (like nicotine in cigarettes) but can treat addiction in another (like the nicotine patch).

I am a professor of pharmacology, and I...

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