Should there be a microbiological specification for marijuana?

Microbiological safety, along with chemical purity and efficacy, is a requirement for most medicinal products (and certainly those which require U.S. FDA and EMA approval.) U.S. Federal Drug Enforcement Administration, Western States including Colorado, Alaska, Oregon and Washington have legalized the sale of powdered cannabis for both recreational and medical use. Because marijuana is classified as a Schedule I drug “having no medical use, with a high potential for abuse,” there is no requirement for the drug to have either a maximum number of permitted microorganisms or for it to have the absence of specific pathogenic organisms. In an insightful article for American Pharmaceutical Review (“Microbiological Attributes of Powdered Cannabis”), Tony Cundell argues that marijuana in the powder form carries a risk of containing microorganisms that can tolerate relatively dry environments (such as fungi) and their toxic by-products. It is relatively easy, the article states, for cannabis to...

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