GW Pharmaceuticals Sativex Trials Disappoint; Signs Deal In Australia

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GW Pharmaceuticals PLC Tuesday said the remaining two Phase 3 trials for its Sativex product were consistent with the first trial in that Sativex did not meet the primary endpoint, although they did show a "statistically significant improvement" for Sativex compared with a placebo.

Sativex is being investigated for the treatment of pain in patients with advanced cancer who experience inadequate analgesia during optimized chronic opioid therapy.

"In light of the missed primary endpoint in the first trial earlier this year, these additional results are not a surprise. Nevertheless, we are encouraged by data across the trials which consistently show positive outcomes for US patients when analysed as a separate cohort," said GW Chief Executive Justin Gover.

"We believe that this finding may provide important guidance in determining the optimal target patient population for Sativex and look forward to a discussion with the FDA on a potential path forward," Gover...

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