How Marijuana Can Affect Autoimmune Diseases
Marijuana has been used as a healing herb since it was discovered, and while the ancients may have had some inkling that it did something to you, thanks to science we now know what its effects are, down to the very molecules and pathways that are affected. In the brain, getting buzzed comes down to (mostly) inhibiting neurotransmitter release. Immune cells don’t get buzzed, but odd things happen nonetheless: histones are modified, meaning that changes to the DNA of these cells are made permanent for subsequent generations. These changes to the DNA alters the expression of inflammatory markers, decreasing them (mostly) and shortening the survival rate of immune cells.
In autoimmune diseases, toning down the immune response is one way to quell the symptoms of the disease. And indeed, for diseases like multiple sclerosis and rheumatoid arthritis, marijuana has marked benefits: it decreases muscle spasticity in multiple sclerosis patients, and limits joint damage...
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