CINCINNATI — The sheer size of Tuesday’s crushing electoral defeat of marijuana legalization in the Buckeye State surprised political experts inside and out of Ohio. Despite a $20 million campaign, the proposed constitutional amendment, known as Issue 3, lost. Amid its smoking wreckage, six reasons emerge to explain what happened to Issue 3 — and what happens next.

With 99% of precincts reporting, the amendment was defeated 64% to 36%.

Call it Not So O-high-o. Voters in the Buckeye State resoundingly rejected an attempt to legalize recreational marijuana by constitutional amendment on Tuesday. But unlike some other cases in which ballot referenda to liberalize drug laws were defeated at the polls, it’s a bit more difficult to draw broad conclusions in Ohio.

Tonight, Ohio voters rejected Issue 3, a referendum on recreational marijuana legalization. The ballot measure served as the only statewide marijuana measure to appear in 2015 and is the first defeat for marijuana advocates since Florida narrowly rejected medical marijuana last November. It is the first loss for a recreational legalization initiative since 2012.

CLEVELAND- Polls are now closed in all but one Ohio county, as boards of elections work to count the ballots.  A last-minute injunction, requested by ResponsibleOhio, extended voting hours in Hamilton County until 9 p.m. That led to Ohio Secretary of State John Husted instructing no county to release statewide election results until 9 p.m. That means no results until at least 9 p.m. in Cuyahoga County as well.

“In order to ensure fairness in the election process, the Secretary has instructed boards of elections to embargo election results from today’s General Election until the polls in Hamilton County close at 9 p.m.,” Husted’s office said.

FunkSac CEO Garett Fortune will be on a plane from Cleveland tonight, probably landing in Denver around the time that Ohio counts up its votes and decides whether to legalize marijuana.

When he touches down, the king of high-tech marijuana bags will have a new round of venture capital funding in his bank account, a new partner in the form of rapper Snoop Dogg, and possibly a new state to conquer.

In fact, if Ohio’s legalization effort succeeds, Fortune will already be able to celebrate, if he chooses. Pot is already legal in Colorado, which is also a major market for Fortune’s business of selling child-proof and odor-proof bags.

Not that he’s sure about how he wants things to turn out in Ohio.

updated Nov. 3, 2015 at 4:29 p.m.

The latest developments in Ohio’s general election as voters decide issues including whether to legalize marijuana (all times EST):

Ballot details

Issue 3: The proposed constitutional amendment would allow adults 21 and older to grow, possess and use pot while making it available for medical use. Home-growers would be limited to four flowering marijuana plants and 8 ounces of usable marijuana at a given time for personal use. Pot sold commercially would have to come from 10 authorized growing sites that are already spoken for.

A Cleveland couple is fighting to regain custody of their newborn daughter following a magistrate's order to have her taken from her parents because the mother was found to have drunk marijuana-based tea to ease her labor pains.

Despite county family services officials recommending that the child remain at home with her parents, Magistrate Eleanore Hilow had baby Nova removed from Hollie Sanford and her husband and placed in the home of one of their relatives.

COLUMBUS, Ohio — The only cannabis legalization-related question on any state ballot this year is in Ohio, where voters were deciding Tuesday whether to legalize marijuana for recreational and medical use in a single stroke.

If it passes, Ohio would become the fifth state to legalize recreational marijuana and would hand over exclusive rights in the state’s cannabis-growing business to a limited circle of private investors that include some famous names.

The proposed constitutional amendment, known as Issue 3, would allow adults 21 and older to grow, possess and use pot while making it available for medical use. Ohioans would be able to buy marijuana, pot-infused candies and other related products from potentially 1,100-plus retail stores.

Ohio to vote on competing marijuana measures Marijuana investors backing Tuesday's legalization vote in Ohio dismissed claims they're trying to monopolize the nascent industry.

"We don't agree with calling it a monopoly," investor Woody Taft told CNN's New Day. "How can you call 10 competing people a monopoly?

Woody and Dudley Taft Jr., who are great-great grandnephews of President Taft, are among the 25 investors in 10 plots of farmland identified in Ohio's Issue 3.

Ahh, Nick Lachey. What has he been up to since his 98 Degrees days? Well, aside from a spot of presenting, some one-off gigs and a new marriage to model/actress/singer Vanessa Minnillo, it seems Lachey has got a bit of a side-project going on. The former US boyband star now owns one of 10 farms that could be allowed to control all large-scale marijuana cultivation in the state of Ohio. Well, that’s if residents vote to legalise marijuana later today.

Nick Lachey: weed kingpin?