The legal marijuana business has created a multibillion-dollar industry, including some interesting side ventures and spinoffs, and even unlikely entrepreneurs have found lucrative niches.

Among them are Deb Baker, a retired high school teacher, and Barb Diner, a former marketing executive, who both live in Denver and have been friends for 27 years. The two had found the relaxed retirement life a bit dull, so they would often bat around ideas that might be interesting to pursue and that could supplement their income.

In 2014, the nascent entrepreneurs saw a niche to be filled — child-resistant marijuana containers that would comply with Colorado’s newly mandated regulation.

Joel Schneider had a long and successful career as a lawyer on Wall Street. "I practiced law for 30 years and hated it."

So once his kids graduated from college, he decided to pursue his passion: Pot.

Now he runs three Bud+Breakfast hotels in Colorado.

"There is no place like this," he said while giving a tour of his first B&B in Denver, a 7,000 square foot home built in 1892 that gives new meaning to "high end."

The six suites range in price from $299 to $399 a night. Guests have included musicians and former NFL players, as well as cannabis fans ages 21 to 80, who enjoy the well-appointed rooms, fully stocked bar, and meals prepared by a chef.

Denver has started work on the nation's first law allowing marijuana clubs and use in public places such as coffee shops or art galleries. But the details about what those pot clubs would look like are very much in the air. Here's what we know, and don't know, about the looming pot clubs headed to Denver:

WHEN WILL THE POT CLUBS OPEN?

Applications are available Friday, but the city has no deadline for issuing the licenses, which will cost $2,000 a year. An informal workgroup made up of police, restaurants, state health authorities and marijuana activists is meeting to suggest regulations for the city licensing authority, but the final call will be made by city regulators.

Those looking for a career in cannabis can check out the Colorado Cannabis Career Summit and Product Showcase on Thursday at the City Hall events venue.

There’s expected to be more than 50 cannabis companies representing upward of 1,000 jobs, according to Vangst, a Denver-based talent agency focused specifically on the marijuana industry.

The summit and showcase take place from 2-8 p.m. Thursday at 144 Broadway. The event is free for people who have a valid MED Occupational License.

According to Rick Byrd, the future of farming is tall, dirtless and local.

Byrd’s vision of skyscraper farms to feed city dwellers begins with a much different kind of crop: marijuana.

An estimated 400,000 Americans are currently living with multiple sclerosis, an autoimmune disease where the body’s immune cells attack a fatty substance called myelin in the nerves. Common symptoms are gait and balance disorders, cognitive dysfunction, fatigue, pain and muscle spasticity.

Colorado has the highest proportion of people living with MS in the United States. It is estimated that one in 550 people living in the state has MS, compared to one in 750 nationally. The reason for this is unknown, but could be related to several factors, such as vitamin D deficiency or environment.

Concentrates can refer to a multitude of products in the world of cannabis – from oil to wax to shatter. The term is a generic way to reference any cannabis product that has been created through the extraction of cannabinoids from the plant.

Concentrates are growing in popularity and are generally considered some of the most refined cannabis products. Although a few forms of concentrates have been used all over the world for hundreds of years, many are recent innovations created to meet the demands of a newly-legalized mass market.

New public service announcements in Colorado aim to keep people’s attention on using marijuana and marijuana-related products safely and responsibly.

The Marijuana Industry Group (MIG), a trade association representing marijuana businesses, is backing the campaign. MIG touts itself as the oldest and largest trade association for legal and licensed cannabis businesses.

The campaign seeks to make people aware they need to take precautionary measures when using cannabis to ensure the safety of themselves and others.

Denver is starting work on becoming the first city in the nation to allow marijuana clubs and public pot use in places such as coffee shops, yoga studios and art galleries.

Voters narrowly approved the "social use" measure last November. But the ballot proposal didn't spell out many rules for how the marijuana could be consumed, beyond saying that the drug can't be smoked inside and that patrons must be over 21.

A workgroup made up of Denver business owners, city pot regulators and marijuana opponents starts work Wednesday on suggesting regulations.

The state Liquor Control Board already has decreed that no businesses with a liquor license can allow marijuana use. That leaves it to restaurants that don't serve alcohol and other event spaces.

For now—and for at least the near future—Denver is America’s de-facto capital for recreational cannabis. It was the first, and until California or Las Vegas get their acts together, it remains the biggest show around.

As such, “Denver” is dangled in front of fearful, parochial City Councils and excitable NIMBYs as a cautionary tale of damage done by legal marijuana sales—apparently, “jobs” and “tax revenue” aren’t for everybody—and alternately held up as a model for how other cities can seize a piece of the weed billions for themselves.

One thing other cities won’t do, if they choose to follow Denver’s lead, is close up shop early.